A Phase 3 Randomized Study Comparing Teclistamab in Combination with Daratumumab SC and Lenalidomide (Tec-DR) and Talquetamab in Combination with Daratumumab SC and Lenalidomide (Tal-DR) versus Daratumumab SC, Lenalidomide, and Dexamethasone (DRd) in Participants with Newly Diagnosed Multiple Myeloma Who are Either Ineligible or not Intended for Autologous Stem Cell Transplant as Initial Therapy 

A Phase III randomized, open-label, international, multicenter study evaluating the efficacy and safety of mosunetuzumab plus lenalidomide in comparison to anti-CD20 monoclonal antibody plus chemotherapy in subjects with previously untreated FLIPI 2-5 follicular lymphoma

Improvement of functional outcome for patients with newly diagnosed grade II or III glioma with co-deletion of 1p/19q – IMPROVE CODEL: the NOA-18 trial

Preoperative radiotherapy versus postoperative radiotherapy after neoadjuuvant chemotherapy ("NeoRad") in high-risk breast cancer: a prospective, randomized, international, multicenter Phase III trial

A Randomized, Placebo-Controlled, Double-Blind, Multicenter, Phase 3 Trial of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Treatment-Naive Metastatic Pancreatic Ductal Adenocarcinoma

Randomized multi-centre open-label non-inferiority phase 3 clinical trial for patients with a stage IV childhood renal tumor comparing upfront Vincristine, Actinomycin-D and Doxorubicin (VAD, standard arm) with upfront Vincristine, Carboplatin and Etoposide (VCE, experimental arm)

Eine internationale prospektive Studie zum klinischen Hochrisiko-Medulloblastom (HR-MB) bei Patienten, die älter als 3 Jahre sind

Internationale, prospektive "Umbrella" Studie incl. einer randomisierten Phase III-Studie zur Frage der Nichtunterlegenheit von 3 Kursen Hochdosis-Chemotherapie verglichen mit fokaler Radiotherapie + Standard-Chemotherapie in der Konsolidierung nach einer konventionellen Induktions-Chemotherapie für Kinder mit einem ATRT im Alter von 12 - 35 Monaten zum Zeitpunkt der Bestrahlung